Croll, Susan D., Ph.D.

Associate Professor

Education: Ph.D. City University of New York (Neuropsychology)

Email: susan.croll@qc.cuny.edu
Office: Razran 215
Telephone: 718-997-3551

Lab: Razran 269
Telephone: 718-997-3554

Ph.D. Program Courses:
Psy 708.3, Psychopharmacology

Undergraduate Courses:
Psy 107, Psychological Statistics
Psy 213W, Experimental Psychology
Psy 352, Psychopharmacology
MNSci 113, Contemporary Issues in Science

Selected Publications:
Nicoletti J.N., Shah, S.K., Goodman J.H., McCloskey, D., Elkady A., Khalid, S., Hylton D.A., Rudge J.S., Scharfman, H.E., Croll S.D. (2008) Vascular endothelial growth factor (VEGF) is upregulated after status epilepticus and serves a neuroprotective role. Neuroscience, 151(1):232-241.

Kasselman L.J., Kintner J., Sideris A., Pasnikowski E., Krellman J.W., Shah S., Rudge J.S., Yancopoulos G.D., Wiegand S.J., Croll S.D. (2007) Dexamethasone Treatment and ICAM-1 Deficiency Impair VEGF-Induced Angiogenesis in Adult Brain. The Journal of Vascular Research, 44(4):283-291.

Kasselman L.J., Sideris A., Bruno C., Perez W.R., Cai N., Nicoletti J.N., Wiegand S.J., Croll S.D. (2006) BDNF: A missing link between sympathetic dysfunction and inflammatory disease? The Journal of Neuroimmunology, 175(1-2):118-127.

MacClosky D.P., Croll, S.D., Scharfman H.E. (2005) Vascular endothelial growth factor (VEGF) decreases in vitro hippocampal glutamatergic excitability. The Journal of Neuroscience, 25(39):8889-8897.

Croll, S.D., McCloskey, D.P., Nicoletti, J.N. & Scharfman, H.E. (2005) VEGF as a seizure therapeutic: Killing Two Birds with One Stone. In D.K. Binder & H.E. Scharfman (Eds.), Growth Factors and Epilepsy, Nova Sciences: New York.

Scharfman H.E., Goodman J.H., MacLeod A., Phani S., Antonelli C. & Croll S.D. (2005) Increased neurogenesis and ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Experimental Neurology, 192(2):348-56.

Barnea, A., Roberts, J. & Croll, S.D. (2004) Continuous exposure to brain-derived neurotrophic factor (BDNF) is required for persistent activation of TrkB receptor, the ERK signaling pathway, and the induction of neuropeptide Y (NPY) production. Brain Research 1020 (1-2):106-117.

Croll, S.D., Ransohoff, R.M., Cai, N., Zhang, Q., Martin, F.J., Wei, T., Kasselman, L.J., Kintner, J., Murphy, A.J., Yancopoulos, G.D. & Wiegand, S.J. (2004) VEGF-mediated inflammation precedes angiogenesis in adult brain. Experimental Neurology, 187(2):388-402.

Croll, S.D., Goodman, J.H., & Scharfman, H.E. (2004) VEGF in Epilepsy: A Double-Edged Sword? In Molecular Mechanisms of Epileptogenesis, Scharfman, H.E. and Binder, D.K., Eds., Landes Bioscience.

Scharfman, H.E., Goodman, J.H., Sollas, A.L., & Croll, S.D. (2002) Spontaneous limbic seizures after intrahippocampal infusion of brain-derived neurotrophic factor (BDNF). Experimental Neurology, 174, 201-214.

Croll, S.D. & Wiegand, S.J. (2001) Vascular growth factors in cerebral ischemia. Molecular Neurobiology, 23(2/3), 121-135.

Binder, D.K., Croll, S.D., Gall, C.M. & Scharfman, H.E. (2001) BDNF and epilepsy: Too much of a good thing? Trends in Neurosciences, 24(1), 47-53.

Research Summary:
Our laboratory is interested in the role of protein factors in neurological and neuropsychiatric disease. We are especially interested in those protein factors with demonstrated trophic effects on neurons, vascular endothelial cells, perivascular cells, and immune cells, as our laboratory has a special interest in the complex interactions between these cell types in disease states. While we are interested in multiple neurological and neuropsychiatric disorders, our current emphases are on epilepsy, dementia, autoimmune, and autistic-like disorders.

Doctoral Students:
Jennifer Johnson
Jason Krellman
Jamee Nicoletti
Elisa Salerni