Faculty/Research
Berman, Doreen, Ph.D.
Bodnar, Richard J., Ph.D.
Borod, Joan C., Ph.D.
Bruder, Gerard, Ph.D.
Brumbaugh, Claudia, Ph.D.
Brumberg, Joshua, Ph.D.
Croll, Susan D., Ph.D.
Ehrlichman, Howard, Ph.D.
Farrell, William, Ph.D.
Fields, Lanny, Ph.D.
Flory, Janine, Ph.D.
Foldi, Nancy, Ph.D.
Foxe, John, Ph.D.
Golub, Sarit, Ph.D.
Gomes, Hilary, Ph.D.
Halperin, Jeffrey, Ph.D.
Hinton, Veronica, Ph.D.
Johnson, Ray, Jr., Ph.D.
Kest, Benjamin, Ph.D.
Kluger, Alan, Ph.D.
Li, Andrea, Ph.D.
Lizardi, Humberto, Ph.D.
Pytte, Carolyn L., Ph.D.
Rabin, Laura, Ph.D.
Ranaldi, Robert, Ph.D.
Ravdin, Lisa, Ph.D.
Sclafani, Anthony, Ph.D.
Sneed, Joel, Ph.D.
Sturmey, Peter, Ph.D.
Walder, Deborah, Ph.D.
Kest, Benjamin, Ph.D.
Associate Professor
Education: Ph.D. City University of New York (Neuropsychology)
Email: kest@mail.csi.cuny.edu
Office: Building 4S Room 205@ College of Staten Island
Telephone: 718-982-4070
Fax : 718.982.4114
Lab:
Telephone: 718-997-3594
PhD Courses:
Psych 70830 Neurochemistry/Psychopharmacology
Selected Publications:
Juni, A., Klein, G., Pintar, J. E., & Kest, B. (2007). Nociception increases during opioid infusion in opioid receptor triple knock-out mice. Neuroscience, 147, 439-444.
Bodnar, R. J., Lewis, S. R., & Kest, B. (2007). Feeding and Drinking. In: Handbook of Behavioral Genetics of the Mouse. Volume I. Genetics of Behavioral Phenotypes (Eds.: W.E. Crusio, F. Sluyter, R.T. Gerlai) Cambridge University Press, New York.
Juni, A., Klein, G., & Kest, B. (2006). Morphine hyperalgesia in mice is unrelated to opioid activity, analgesia, or tolerance: evidence for multiple diverse hyperalgesic systems. Brain Research, 1070, 35-44.
Klein, G., Rossi, G., Juni, A., Inturrisi, C. E., & Kest, B. (2006). An antisense nucleotide targeting exon 1 of the mu opioid receptor gene attenuates heroin dependence but not analgesia in mice. Society for Neuroscience Abstracts 32.
Olofsen, E., Romber, R., Bijl, H., Mooren, R., Engbers, F., Kest, B., & Dahan, A. (2005). Alfentanil and placebo analgesia: no sex differences detected in models of experimental pain. Anesthesiology, 103, 130-139.
Kest, B., Palmese, C., Juni, A., Chesler, E. J., & Mogil, J. S. (2004). Mapping of a quantitative trait locus for morphine withdrawal severity. Mammalian Genome, 15, 610-617.
Research Summary:
My laboratory studies pain and its modulation by opioids such as heroin and morphine in mice. We are particularly interested in studying how pain and opioid sensitivity is influenced by sex and genetic background, and perform studies that attempt to identify which genes and hormones contribute to differences between individuals by utilizing males and females of genetically defined strains, gene mapping, and antisense strategies. Since extended opioid use is also associated with dependence, similar studies are conducted on sex and genetic differences during opioid withdrawal.
Lab Members:
PhD Students:
Gad Klein
Aaron Juni
Bill Kowalczyk
Amanda Waxman